Summary of current Basic Science Research initiatives and interactions:

1. T cells as markers of scleroderma disease activity and outcome.
   Dr. Francesco Boin
2. Vascular smooth muscle cell biology and expression of scleroderma autoantigens.
   Drs. Livia Casciola-Rosen, Antony Rosen and others
3. The biology of progenitor cells in scleroderma.
   Drs. Livia Casciola-Rosen, Antony Rosen and others
4. The interface of the immune response, blood vessels, and extra-cellular matrix.
   Drs. Livia Casciola–Rosen, Antony Rosen, Nicholas Flavahan, and Dr. Michael Simons at Dartmouth College
5. Biology of scleroderma lung disease.
   Dr. Sergei Atamas at University of Maryland and Dr. Francesco Boin
6. The biology of the microvascular disease of scleroderma.
   Dr. Nicholas Flavahan
7. Angiogenesis and the pathogenesis of scleroderma.
   Dr. Laura Hummers and Dr. Michael Simons at Dartmouth
8. Gene Arrays: A method to probe the pathogenesis of scleroderma.
   Dr. Laura Hummers and Dr. Whitfield at Dartmouth
9. The biology of Pulmonary Arterial Hypertension in scleroderma.
   Dr. Paul Hassoun and others
10. The genomics of scleroderma.
    Dr. Kathleen Barnes and others